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Fluvoxamine study #6 of 7   All Outcomes
8/12 Late treatment study
Németh et al., SSRN, doi:10.2139/ssrn.3896539 (Preprint)
Fluoxetine May Improve Survival of Patients with COVID-19 Pneumonia: A Retrospective Case-Control Study
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Retrospective 269 hospitalized patients in Hungary, 110 treated with fluoxetine, showing lower mortality with treatment.
Németh et al., 8/12/2021, retrospective, Hungary, Europe, preprint, 6 authors.
risk of death, 67.0% lower, RR 0.33, p < 0.001, treatment 15 of 110 (13.6%), control 49 of 159 (30.8%), adjusted per study, odds ratio converted to relative risk, multivariable logistic regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
All 7 studies   All Outcomes
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