Association Between the Use of Psychotropic Medications and the Risk of COVID-19 Infection Among Long-term Inpatients With Serious Mental Illness in a New York State–wide Psychiatric Hospital System
Nemani et al., JAMA Network Open, doi:10.1001/jamanetworkopen.2022.10743
Retrospective 1,958 consecutive psychiatric patients in the USA, showing higher cases and lower mortality with fluvoxamine, without statistical significance, and there was only 25 fluvoxamine patients.
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risk of death, 97.5% lower, RR 0.03, p = 1.00, treatment 0 of 16 (0.0%), control 38 of 953 (4.0%), NNT 25, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
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risk of case, 29.8% higher, RR 1.30, p = 0.16, treatment 16 of 25 (64.0%), control 953 of 1,933 (49.3%).
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Nemani et al., 5/6/2022, retrospective, USA, North America, peer-reviewed, 12 authors, study period 8 March, 2020 - 1 July, 2020.