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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Hospitalization 7% Improvement Relative Risk c19fluvoxamine.com/lenze2.html Favors fluvoxamine Favors control
20 August 2021 - Early treatment study
Fluvoxamine for Early Treatment of COVID-19: The STOP COVID Clinical Trials
Lenze, E. (News)
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Presentation noting that STOP COVID 2 was terminated early for futility with only 30/551 cases of detioration and no significant treatment effect. The main results are not available yet, however partial results presented suggest that early treatment was more effective. NCT04668950. Hospitalization results are from [1].
risk of hospitalization, 7.3% lower, RR 0.93, p = 1.00, treatment 11 of 272 (4.0%), control 12 of 275 (4.4%), NNT 313.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Lenze et al., 8/20/2021, Double Blind Randomized Controlled Trial, USA, North America, preprint, 1 author, average treatment delay 5.0 days.
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