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0 0.5 1 1.5 2+ Death/intubation 42% Improvement Relative Risk c19fluvoxamine.com Hoertel et al. Fluvoxamine for COVID-19 Prophylaxis Favors fluvoxamine Favors control
Hoertel, 2,846 patient fluvoxamine prophylaxis study: 42% lower combined mortality/intubation [p<0.0001] https://c19p.org/hoertel3
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Association Between FIASMAs and Reduced Risk of Intubation or Death in Individuals Hospitalized for Severe COVID-19: An Observational Multicenter Study
Hoertel et al., Clinical Pharmacology & Therapeutics, doi:10.1002/cpt.2317
29 May 2021    Source   PDF   Share   Tweet
Retrospective 2,846 severe COVID-19 patients in France, 277 taking a FIASMA medication, showing lower risk of intubation of death with FIASMA use.
risk of death/intubation, 42.0% lower, RR 0.58, p < 0.001, treatment 104 of 277 (37.5%), control 1,064 of 2,569 (41.4%), adjusted per study, IPW multivariable Cox regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hoertel et al., 5/29/2021, retrospective, France, Europe, peer-reviewed, 78 authors.
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