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0 0.5 1 1.5 2+ Mortality 42% Improvement Relative Risk c19fluvoxamine.com Calusic et al. Fluvoxamine for COVID-19 ICU Favors fluvoxamine Favors control
Calusic, 102 patient fluvoxamine late treatment PSM study: 42% lower mortality [p=0.03] https://c19p.org/calusic
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Safety and efficacy of fluvoxamine in COVID-19 ICU patients: an open label, prospective cohort trial with matched controls
Calusic et al., British Journal of Clinical Pharmacology, doi:10.1111/bcp.15126
1 Nov 2021    Source   PDF   Share   Tweet
Prospective PSM study of 51 COVID-19 ICU patients in Croatia and 51 matched controls, showing significantly lower mortality with treatment.
risk of death, 42.0% lower, HR 0.58, p = 0.03, treatment 30 of 51 (58.8%), control 39 of 51 (76.5%), NNT 5.7, adjusted per study, propensity score matching.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Calusic et al., 11/1/2021, prospective, propensity score matching, Croatia, Europe, peer-reviewed, 7 authors, study period 1 April, 2021 - 31 May, 2021.
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Late treatment
is less effective
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